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產(chǎn)品規(guī)格
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BN41776R-50ul
50ul
￥1486.00
交叉反應(yīng)：Human,Mouse,Rat,Pig(predicted:Chicken,Dog,Cow,Horse,Rabbit,Sheep,GuineaPig) 推薦應(yīng)用：WB,IHC-P,IHC-F,IF,ELISA
BN41776R-100ul
100ul
￥2360.00
交叉反應(yīng)：Human,Mouse,Rat,Pig(predicted:Chicken,Dog,Cow,Horse,Rabbit,Sheep,GuineaPig) 推薦應(yīng)用：WB,IHC-P,IHC-F,IF,ELISA
BN41776R-200ul
200ul
￥3490.00
交叉反應(yīng)：Human,Mouse,Rat,Pig(predicted:Chicken,Dog,Cow,Horse,Rabbit,Sheep,GuineaPig) 推薦應(yīng)用：WB,IHC-P,IHC-F,IF,ELISA
產(chǎn)品描述
| 英文名稱 | Heme Oxygenase 1 |
| 中文名稱 | 血紅素氧合酶 1/熱休克蛋白32抗體 |
| 別 名 | Heme oxygenase (decycling) 1; Heme oxygenase 1; Hemox; HMOX 1; Hmox; HMOX1; HO 1; HO-1; HO; HO1; Hsp32; bK286B10; D8Wsu38e; HMOX1_HUMAN. |
| 研究領(lǐng)域 | 腫瘤 心血管 免疫學(xué) 神經(jīng)生物學(xué) 信號轉(zhuǎn)導(dǎo) 表觀遺傳學(xué) Alzheimer's |
| 抗體來源 | Rabbit |
| 克隆類型 | Polyclonal |
| 交叉反應(yīng) | Human, Mouse, Rat, Pig, (predicted: Chicken, Dog, Cow, Horse, Rabbit, Sheep, Guinea Pig, ) |
| 產(chǎn)品應(yīng)用 | WB=1:500-2000 ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 （石蠟切片需做抗原修復(fù)） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 分 子 量 | 32kDa |
| 細(xì)胞定位 | 細(xì)胞漿 |
| 性 狀 | Liquid |
| 濃 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human HO-1:101-200/288 |
| 亞 型 | IgG |
| 純化方法 | affinity purified by Protein A |
| 儲 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
| 保存條件 | Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. |
| PubMed | PubMed |
| 產(chǎn)品介紹 | The hemeoxygenase-1 calls that the hemoglobin oxidizes to synthesize the enzyme again-1( hemeoxygenase-1, HO-1) is the catalyst enzyme that a kind of hemoglobin declines the solution, under the NADPH and the cell dye P-450 revivification enzymes and the member oxygen functions, the catalyst HO-1 hemoglobin declines the solution as the courage green vegetable, CO and irons, the former revivification has the very strong anti- to oxidize the ability after become the red vegetable of courage , the latter is a kind of important letter to make the member. Function: Heme oxygenase cleaves the heme ring at the alpha methene bridge to form biliverdin. Biliverdin is subsequently converted to bilirubin by biliverdin reductase. Under physiological conditions, the activity of heme oxygenase is highest in the spleen, where senescent erythrocytes are sequestrated and destroyed. Subcellular Location: Microsome. Endoplasmic reticulum. Tissue Specificity: Expressed at higher levels in renal cancer tissue than in normal tissue (at protein level). DISEASE: Defects in HMOX1 are the cause of heme oxygenase 1 deficiency (HMOX1D) [MIM:614034]. A disease characterized by impaired stress hematopoiesis, resulting in marked erythrocyte fragmentation and intravascular hemolysis, coagulation abnormalities, endothelial damage, and iron deposition in renal and hepatic tissues. Clinical features include persistent hemolytic anemia, asplenia, nephritis, generalized erythematous rash, growth retardation and hepatomegaly. Similarity: Belongs to the heme oxygenase family. SWISS: P09601 Gene ID: 3162 Database links: Entrez Gene: 3162 Human Entrez Gene: 15368 Mouse Omim: 141250 Human SwissProt: P09601 Human SwissProt: P14901 Mouse Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
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